Developing Rapid Diagnostics for Saliva

We are developing a versatile multiplexing (self referencing) detection platform for SARS-CoV-2 detection in saliva. The system integrates signals from different biorecognition elements for rapid detection of multiple variants (intact virion particle). Laser inscribed graphene electrodes are combined with open channel microfluidics and signals is acquired using a smartphone (Bluetooth connection for security purposes). The development of a functional and reliable multiplex biosensor system will be useful for addressing longstanding needs in public health as the respiratory Coronavirus family continues its seasonal visits, which may repeat over an unknown time span.